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March 22, 337: Constantine, the first Christian emperor of Rome, dies at age 47. As emperor, he issued an edict officially tolerating Christianity, though he did little to stave off paganism. He also summoned the Council of Nicea to settle the Arian dispute over the nature of Christ (see issue 57: The Conversion of Rome).

March 22, 1638: Religious dissident Anne Hutchinson is expelled from Massachusetts Bay Colony. Questioned about her teachings on grace, she insisted she had received divine revelations. When her examiners asked how she knew these came from God, she replied, "How did Abraham know that it was God that bid him offer his son, being a breach of the Sixth Commandment?" Although Hutchinson repented of her "errors," her questioners decided she was lying and banished her from the colony (see issue 41: American Puritans).

March 22, 1758: Jonathan Edwards, America's greatest theologian, dies from the effects of a smallpox vaccination after arriving in New Jersey to accept the presidency of what is now Princeton University (see issue 8: Jonathan Edwards and issue 77: Jonathan Edwards).

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