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May 22, 337: Constantine, the first Christian emperor of Rome, dies. Though known for calling the Council of Nicea (which condemned the Arian heresy) and for beginning the process of Christianizing the empire, he waited until just before his death before he finally accepted baptism into the church (see issue 57: Converting the Empire).
May 22, 452: Leo, bishop of Rome, sends three angry letters to protest the Council of Chalcedon's recent elevation of Constantinople to the preeminent see in Christendom. ...
