October 21, 1555: Finding that the recent martyrdom of bishops Nicholas Ridley and Hugh Latimer had intensified Protestant zeal, Queen Mary launches a series of fierce persecutions in which more than 200 men, women, and children were killed (see issue 48: Thomas Cranmer).
October 21, 1663: Virginia colonist John Harlow is fined 50 pounds of tobacco for missing church.
October 21, 1692: William Penn is deposed as governor of Pennsylvania. His grateful overtures to James II for permitting religious freedom for Dissenters from the Church of England led William and Mary to charge Penn with being a papist. They were also troubled by his pacifism.