June 22, 431: The Third Ecumenical Council opens in Ephesus to condemn Nestorianism, which holds that Christ was two separate persons rather than one person with two natures (see issue 51: Heresy in the Early Church).

June 22, 1714: Matthew Henry, English Presbyterian pastor and Bible commentator, dies. His work is still published as Matthew Henry's Commentary.

June 22, 1750: Colonial preacher Jonathan Edwards is dismissed from his Massachusetts pastorate for pursuing tests for church membership (see ...