Renée of Ferrara sheltered Protestant refugees, wrote bold letters to Calvin and other reformers, and courted the wrath of her own family. But restrictions on women's roles prevented her from having a wider influence.
August 3, 1492: Christopher Columbus sets sail from Spain for the "Indies." Though the explorer was in part driven by a quest for gold and glory, he also saw himself as a missionary. He thought, if there were a shortcut to the East by sea, missionaries could be sent there faster, thus enabling Christians to meet the provision for world evangelization before the Lord could return (see issue 35: Christopher Columbus).